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Nanyang Technological University

单位所在地区:其它地区-其它地区 | 单位行业:高校/科研机构 | 单位规模:10000人以上

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Our interdisciplinary research groups work on complex regulations of actin remodeling during signal transduction under physiological and pathological conditions. We study molecular mechanisms by which biomolecular phase separation finetunes physical-chemical properties of the macromolecular complex to reorganize actin polymerization by tuning the biochemical activities in the membrane-associated membrane-less organelles. We also focus on the mechanisms of mechanosensing and mechanotransduction, by which cell wall (CW) – plasma membrane (PM) – actin cytoskeleton (AC) continuum regulates molecular dynamics and functions of the integrated biomolecules through tunning their molecular condensation and thereby modulates cellular signal transductions. 

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